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Welcome to Skincarma.

These are the musings of Carmine Montalto, NYC-based writer, skincare junkie and brand guru. The former copywriter at Kiehl’s, Carmine has more than 25 years of experience in beauty. Through the Skincarma Blog, he puts all of his product wisdom to work demystifying the ever-evolving world of skin care. 

You can change your skin’s destiny.™

PRODUCT REVIEW: ONE SKIN OS-01 TOPICAL SUPPLEMENT - BEST PEPTIDE FACE CREAM, BEST ANTI-AGING MOISTURIZER WITH PEPTIDES

ONE SKIN | OS-01 TOPICAL SUPPLEMENT 

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I’m pretty sure what I’ve got here is alien technology. One Skin’s OS-01 Topical Supplement looks like a futuristic device without a user’s manual. One wrong move and I could send myself into an alternate universe.

One Skin describes their cool innovation as “the first topical supplement of its kind designed to extend your skinspan by improving skin health and skin strength.”

The brand’s proprietary OS-01 peptide (found in the INCI as Decapeptide-52) was developed by a team of four female scientists. (What planet are they from?)

Clinical testing has demonstrated that the OS-01 peptide helps to regenerate the skin, meaning it accelerates what the skin does well on its own when we are young. As we age, our skin grows more sluggish — along with the rest of us. Some days I barely want to get off the couch!

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PRODUCT REVIEW: AUGUSTINUS BADER THE CREAM - WWD'S "THE 100 GREATEST SKINCARE PRODUCTS OF ALL TIME"

According to the brand: “Through our clinical studies, OneSkin discovered its ability to reverse the biological age of one’s skin by reducing the main drivers of inflammation that lead to skin cell malformation and death (i.e. wrinkles, loss of elasticity, and aging skin).”

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What Are Peptides?

Peptides are among the most mysterious of skincare actives — and perhaps the least understood. But what are peptides, exactly. Simply, they are protein fragments composed of amino acids and are naturally found in the skin.

There’s an excellent article from the experts on the Paula’s Choice Research Team that goes quite the distance in explaining what peptides are and their multitude of skin benefits titled simply, Peptides for Skin. You can catch the full piece here.

What Are Peptides?

First, we need to start with the science: Peptides are fragments of proteins. On their own, peptides are made up of amino acids. When amino acids are combined in certain formations they create specific peptides (and there are hundreds of peptides), and when peptides are formed in a certain way, they make specific proteins.

Proteins are the fundamental building blocks of skin. Without peptides, skin doesn’t remain intact and the result is loss of firmness, appearance of wrinkles, texture changes, and skin that doesn’t bounce back as it once did.

What’s so fascinating about peptides is that abundant research has clearly shown that each of them works in very specific ways to target an exact skin care need. They also teach skin to do what's required to help revitalize these building blocks, which can help revive aging skin.


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Aside from the formula’s alien peptide, what else is going on in this light, silky lotion?

There are multiple forms of the power humectant Hyaluronic Acid to hydrate the skin. Plus, there’s a treasure trove of antioxidant plant oils including Grape Seed Oil and Rosehip Oil.

Curiously, the third ingredient is one I’d never seen before: Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato). I thought I’d discovered more alien technology until I googled it. It’s an extract popular in herbal medicine from the Amazon and derived from the Amazonian “Tree of Youth”. According to the US National Library of Medicine, it has anti-aging, antioxidant, antimicrobial, emollient, wound healing, hemostatic, contraceptive, stimulant, and anti-diabetic properties.

Beam me up, Scotty…

SHOP THE BLOG: Purchase the One Skin OS-01 Topical Supplement for $120 here.


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A COMPLETE $100 SKINCARE ROUTINE WITH THE INKEY LIST, THE ORDINARY, BENTON & MORE!

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The Ingredient List of the One Skin OS-01 Topical Supplement:

Water (Aqua), Glycerin, Calycophyllum Spruceanum Bark Oleic Extract (Pau Mulato), Sorbitan Olivate, Cetearyl Olivate, Squalane, Carapa Guianensis Seed (Andiroba) Oil, Vitis Vinifera (Grape) Seed Oil, Pentaclethra Macroloba (Pracaxi) Oil, Rosa Canina (Rose hips) Fruit Oil, Prunus Domestica (Plum) Seed Oil, Caprylhydroxamic Acid, Glyceryl Caprylate, Decapeptide-52*, Hyaluronic Acid, Sodium Hyaluronate, Sodium Hyaluronate Crosspolymer, Niacinamide, Allantoin, Bentonite, Tocopheryl Acetate, Tocopherol, Cellulose, Cetyl Palmitate, Sorbitan Palmitate, Xanthan Gum, Potassium Sorbate, Phenoxyethanol, Sorbic Acid, Caprylyl Glycol, Tetrasodium Glutamate Diacetate. *OS-01 Peptide

PRODUCT REVIEW: SYMBIOME POSTBIOMIC FACIAL OILS – BEST FACIAL OILS FOR DRY SKIN, BEST PROBIOTIC FACE CREAM FOR THE MICROBIOME

PRODUCT REVIEW: SYMBIOME POSTBIOMIC FACIAL OILS – BEST FACIAL OILS FOR DRY SKIN, BEST PROBIOTIC FACE CREAM FOR THE MICROBIOME

PRODUCT REVIEW: KAT BURKI GOJI ESSENCE - BEST LACTIC ACID TREATMENT, BEST FERMENTED ESSENCE

PRODUCT REVIEW: KAT BURKI GOJI ESSENCE - BEST LACTIC ACID TREATMENT, BEST FERMENTED ESSENCE